@gsuberland I think this motherboard specifies that regardless of memory rank it all is able to run at the same maximum 2966Mhz (although because of my CPU 2400Mhz will be the maximum speed)

Any idea of what kind of performance loss I can expect from dual rank? It would save me roughly 150 euros (on 8x16gb of memory), but I'm not sure if it's worth it. CPU would run in a Six-Channel configuration (6x16GB per CPU), but I'm not running anything memory specific, I just want to optimize performance where possible :)

@Purple the performance loss is pretty miminal, to the point where it's probably statistically insignificant for your average workload.

the reason the single rank DIMMs are more expensive is that they have to use higher density DRAM ICs to reduce the capacitive loading, which makes them useful on 4DPC boards. but it looks like your board and CPU should handle this fine here.